Matches in SemOpenAlex for { <https://semopenalex.org/work/W2379861223> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2379861223 abstract "Objective To detect the expression level of miR-182 in colorectal cancer,explore the correlations between miR-182 expression and clinicopathological features,and investigate its effect on the migration of colorectal cancer cells in vitro.Methods Quantitative real-time PCR(qRT-PCR) was used to measure the expression of miR-182 in 86 pairs of colorectal cancer and corresponding adjacent noncancerous tissues,and the correlations between miR-182 expression and clinicopathological features were further analyzed.HT-29 cells were transiently transfected with miR-182 mimics and miR-negative control,and the experiment was divided into miR-182 over-expression group,negative control group and blank group.In addition,the migration ability was detected by transwell assay in vitro.Results The expression of miR-182 was significantly higher in colorectal cancer tissues compared with corresponding adjacent noncancerous tissues(P0.001).Its level was significantly correlated with local invasion(P=0.028),lymph nodes metastasis(P=0.003),distant metastasis(P=0.006),and clinical stage(P=0.005),respectively.However,no correlation was observed between miR-182 and age or other clinicopathological parameters(all P0.05).The migration cells were significantly higher in miR-182 over-expression group than negative control group and blank group.Conclusion MiR-182 is up-regulated in colorectal cancer and that high miR-182 expression is associated with the metastasis and progression of colorectal cancer.In addition,the up-regulated miR-182 promotes colorectal cancer cell migration in vitro,suggesting a potential target for the prevention and therapy of metastasis in colorectal cancer." @default.
- W2379861223 created "2016-06-24" @default.
- W2379861223 creator A5024677474 @default.
- W2379861223 date "2013-01-01" @default.
- W2379861223 modified "2023-09-23" @default.
- W2379861223 title "Expression of miR-182 in colorectal cancer and its effect on the migration of colorectal cancer cells" @default.
- W2379861223 hasPublicationYear "2013" @default.
- W2379861223 type Work @default.
- W2379861223 sameAs 2379861223 @default.
- W2379861223 citedByCount "0" @default.
- W2379861223 crossrefType "journal-article" @default.
- W2379861223 hasAuthorship W2379861223A5024677474 @default.
- W2379861223 hasConcept C104317684 @default.
- W2379861223 hasConcept C121608353 @default.
- W2379861223 hasConcept C126322002 @default.
- W2379861223 hasConcept C143998085 @default.
- W2379861223 hasConcept C145059251 @default.
- W2379861223 hasConcept C202751555 @default.
- W2379861223 hasConcept C2779013556 @default.
- W2379861223 hasConcept C3019926457 @default.
- W2379861223 hasConcept C48023723 @default.
- W2379861223 hasConcept C502942594 @default.
- W2379861223 hasConcept C526805850 @default.
- W2379861223 hasConcept C55493867 @default.
- W2379861223 hasConcept C71924100 @default.
- W2379861223 hasConcept C86803240 @default.
- W2379861223 hasConceptScore W2379861223C104317684 @default.
- W2379861223 hasConceptScore W2379861223C121608353 @default.
- W2379861223 hasConceptScore W2379861223C126322002 @default.
- W2379861223 hasConceptScore W2379861223C143998085 @default.
- W2379861223 hasConceptScore W2379861223C145059251 @default.
- W2379861223 hasConceptScore W2379861223C202751555 @default.
- W2379861223 hasConceptScore W2379861223C2779013556 @default.
- W2379861223 hasConceptScore W2379861223C3019926457 @default.
- W2379861223 hasConceptScore W2379861223C48023723 @default.
- W2379861223 hasConceptScore W2379861223C502942594 @default.
- W2379861223 hasConceptScore W2379861223C526805850 @default.
- W2379861223 hasConceptScore W2379861223C55493867 @default.
- W2379861223 hasConceptScore W2379861223C71924100 @default.
- W2379861223 hasConceptScore W2379861223C86803240 @default.
- W2379861223 hasLocation W23798612231 @default.
- W2379861223 hasOpenAccess W2379861223 @default.
- W2379861223 hasPrimaryLocation W23798612231 @default.
- W2379861223 hasRelatedWork W2009824580 @default.
- W2379861223 hasRelatedWork W2062103524 @default.
- W2379861223 hasRelatedWork W2236841749 @default.
- W2379861223 hasRelatedWork W2341883970 @default.
- W2379861223 hasRelatedWork W2354074040 @default.
- W2379861223 hasRelatedWork W2361002075 @default.
- W2379861223 hasRelatedWork W2366206825 @default.
- W2379861223 hasRelatedWork W2369004632 @default.
- W2379861223 hasRelatedWork W2370262613 @default.
- W2379861223 hasRelatedWork W2375581209 @default.
- W2379861223 hasRelatedWork W2413810312 @default.
- W2379861223 hasRelatedWork W2807780329 @default.
- W2379861223 hasRelatedWork W2953866084 @default.
- W2379861223 hasRelatedWork W2962804733 @default.
- W2379861223 hasRelatedWork W3003660679 @default.
- W2379861223 hasRelatedWork W3028750114 @default.
- W2379861223 hasRelatedWork W3133008933 @default.
- W2379861223 hasRelatedWork W3159926496 @default.
- W2379861223 hasRelatedWork W3173191438 @default.
- W2379861223 hasRelatedWork W3031421272 @default.
- W2379861223 isParatext "false" @default.
- W2379861223 isRetracted "false" @default.
- W2379861223 magId "2379861223" @default.
- W2379861223 workType "article" @default.