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- W2379873062 abstract "Objective To investigate the effect of cis-Diamminedichloroplatinum(DDP) with different dose and time on human telomerase reverse transcriptase(hTERT) mRNA expression in human hepatocellular line BEL-7404and BEL-7404/ADM.Methods The expression of hTERT-mRNA was examined by RT-PCR treated with DDP at different doses after 24 h、48 h and 72 h.Results The hTERT expression was significantly inhibited after treated with the different concentrations of DDP for 48 h、72 h.Compared with BEL-7404/ADM cells,with the concentration and time apparently increased,the hTERT expression began to be inhibited when treated with DDP.Conclusion The expression of hTERT-mRNA can be inhibited by DDP.This effect is dose and time dependent." @default.
- W2379873062 created "2016-06-24" @default.
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- W2379873062 date "2007-01-01" @default.
- W2379873062 modified "2023-09-23" @default.
- W2379873062 title "The Effects of cis-Diamminedichloroplatinum on Human Telomerase Reverse Transcriptase mRNA Expression in Human Hepatocellular Line BEL-7404 and BEL-7404/ADM" @default.
- W2379873062 hasPublicationYear "2007" @default.
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