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- W2379914908 abstract "Objective To evaluate the prevalence of hepatitis C virus (HCV) infection in maintenance haemodialysis (HD) patients and analyze simply its risk factors.Methods Levels of anti-HCV antibody,levels of HCV core antigen,and HCV-RNA in serums of 122 maintenance haemodialysis patients were determined by enzyme-linked immunosorbent assay (ELISA),real-time fluorescent quantificational polymerase chain reaction (PCR) respectively.And aminotransferase were analyzed by enzymatic kinetic method.Results In total,anti-HCV antibody were positive in 36 patients (29.5%) in some of which increased aminotransferase were observed.Positive rate of HCV core antigen was 8.2% (10 out of 122) with HCV antibody negative.HCV-RNA positive occurred in 33 patients (27.0%),while antibody were negative in 6 patients with viraemia.Higher prevalence were observed in patients with experience of blood transfusion and long duration of dialysis.Conclusion HCV wes common in maintenance haemodialysis patients,and the prevalence of it were correlated with blood transfusion and duration of dialysis.Simultaneous detection of anti-HCV antibody,HCV core antigen and HCV-RNA(or two of the three items simultaneously) appears to increase the sensitivity in the diagnosis of HCV infection." @default.
- W2379914908 created "2016-06-24" @default.
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- W2379914908 date "2008-01-01" @default.
- W2379914908 modified "2023-09-26" @default.
- W2379914908 title "Study on Prevalence of Hepatitis C Virus (HCV) Infection in Maintenance Haemodialysis (HD) Patients and Analysis of Its Risk Factors" @default.
- W2379914908 hasPublicationYear "2008" @default.
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