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- W2379939865 abstract "Objective To study the immunophenotypic features of NK/T cell lymphoma in children and its association with Epstein-Barr virus (EBV) infection. Methods Five cases of children′s NK/T cell lymphoma were studied. CD45RO, CD3e, CD56, CD20, TIA-1 and granzyme B were detected by immunohistochemistry staining for investigating immunophenotype. The expression of EBV-latent membrane protein (LMP-1) were detected by immunohistochemistry. EBV-encoded RNA (EBER1/2) were detected by in situ hybridization (ISH). Results CD45RO, CD3e, TIA-1 and granzyme B were positive in 5 cases, CD56 was positive in 2 cases, while CD20 negative in 5 cases.EBER1/2 positive in 4 cases and LMP-1 positive in 3 cases.Conclusions NK/T cell lymphoma in children is strong associated with EBV infection,and EBV infection may play an important role in the pathogenesis of children NK/T cell lymphoma." @default.
- W2379939865 created "2016-06-24" @default.
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- W2379939865 date "2007-01-01" @default.
- W2379939865 modified "2023-09-25" @default.
- W2379939865 title "Immunophenotypic Features of NK/T Cell Lymphoma in Children and Its Association with Epstein-Barr Virus" @default.
- W2379939865 hasPublicationYear "2007" @default.
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