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- W2379967438 abstract "Objective: To observe the effects of Bushen Pingchuan Cream Formula on related cytokine of Th17 in rats' plasma with asthma,and to explore its mechanism in treating asthma. Methods: Sixty SD rats were randomly divided into normal controlled group,untreated group,dexame thasone group,and medicinal extract prevented,medicinal extract treated,and medicinal extract prevented and treated groups,with ten rats in each group. Asthma was induced by intraperitoneal injection of ovalbumin( OVA) and forced inhalation of atomized OVA. Expression of IL- 6,IL- 17 and TGF-β in blood was detected by Elisa method. Results: Expression of IL-6,IL-17 and TGF-β in blood was higher in the untreated group than in the normal controlled group( P 0. 01). Expressions ofIL-6,IL-17 and TGF-βin medicinal extract groups were down regulated as compared with those in the untreated group and dexamethasone group( P 0. 05),and there were no significant differences as compared with the normal controlled group( P 0. 05). Conclusion: Bushen Pingchuan Cream Formula can control and prevent the transformation of Th17,which may be one of its mechanisms in preventing and treating asthma." @default.
- W2379967438 created "2016-06-24" @default.
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- W2379967438 date "2014-01-01" @default.
- W2379967438 modified "2023-09-26" @default.
- W2379967438 title "Regulating Action of Bushen Pingchuan Cream Formula for the Related Cytokine of Th17 in Rats with Bronchial Asthma" @default.
- W2379967438 hasPublicationYear "2014" @default.
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