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- W2379983254 abstract "Objective To investigate the clinical effects of lansoprazole in treatment of reflux esophagitis.Methods 603 patients with reflux esophagitis diagnosed with gastroscopy,which agreed with reexamination after the regular treatment,were randomly divided into treatment group and control group.The patients of treatment group were given each 15mg of lansoprazole b.i.d.PO combined with cisapride t.i.d.PO,but the patients of control group were given each 20mg of famotidine b.i.d.PO combined with cisapride t.i.d.PO.After 8 weeks,gastroscope was performed to study the healing rate and symptom relief rate.Results The total symptom relief rate of the treatment group was 80.1%,but that of typeⅠ,typeⅡand type Ⅲ was 93.3%,82.9% and 72.7% respectively;the total effective rate as shown by gastroscopy was 79.0%,but that of typeⅠ,typeⅡand type Ⅲ was 93.5%,83.8% and 68.2% respectively.The total symptom relief rate of control group was 70.1%,but that of typeⅠ,typeⅡ and type Ⅲ was 84.6%,69.6% and 51.7% respectively;the total effective rate as shown by gastroscopy was 64.9%,but that of typeⅠ,typeⅡ and type Ⅲ was 76.9%,65.9% and 48.3% respectively.The difference between 2 groups was significant.Conclusion Lansoprazole is effective in the treatment of reflux esophagitis." @default.
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- W2379983254 date "2008-01-01" @default.
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- W2379983254 title "A clinical study of lansoprazole in the treatment of reflux esophagitis" @default.
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