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- W2379984055 abstract "Objective: To optimize separation and purification technology of extract of Rhodiola rosea from compound rosavin rapidly disintegrating oral tablets by macroporous resin. Method: Taking contents and recoveries of salidroside and rosavin as indexes,single factor tests were adopted to screen macroporous resin model and optimize its purification process. Result: AB-8 macroporous resin had the best separation efficiency,optimum purification process conditions were as follows: added just the right amount of water to ample dissolution of extract of R. rosea,absorption velocity 2 BV·h- 1,diameter-height ratio 1∶7,adsorption capacity of salidroside and rosavin 7. 18,10. 43 mg·g- 1,washed impurities with water,eluted by 12 BV of 40% ethanol,elution flow rate 4 BV·h- 1,regenerated resin after using three times; Average extraction amounts of salidroside and rosavin were 1. 870% and 3. 186%,average recoveries were 82% and 96. 26%,average purities were 5. 72% and 9. 72%, respectively; Extract yield reduced to 4. 57% from 13. 73%. Conclusion: AB-8 macroporous resin had a good purification effect of salidroside and rosavin,optimized purification process was stable and feasible." @default.
- W2379984055 created "2016-06-24" @default.
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- W2379984055 date "2014-01-01" @default.
- W2379984055 modified "2023-10-01" @default.
- W2379984055 title "Optimization of Purification Process for Extract of Rhodiola rosea from Compound Rosavin Rapidly Disintegrating Oral Tablets by Macroporous Resin" @default.
- W2379984055 hasPublicationYear "2014" @default.
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