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- W2379985474 abstract "It has been more than 40 years since the first full publications on the biological effects of the bisphosphonates,appeared in 1969. Bisphosphonates are the leading drugs used to treat osteoporosis and skeletal complications associated with tumors,especially multiple myeloma and bone metastases. Interestingly,recent studies showed that bisphosphonate,may have the direct effect on reduced mortality risk. The underlying mechanisms may be the effects of bisphosphonates on preventing fracture,improving physiological resilience,preventing frailty,reducing risks of cardiovascular events,or anti-tumor. Furthermore,studies in population with tumors( e. g.,multiple myeloma,colon cancer)showed that patients treating with bisphosphonate had higher survival rate and longer overall survival duration than patients taking placebo. All of these results show us a new perspective of bisphosphonate in clinical application. How to further prove these results will be our next important step." @default.
- W2379985474 created "2016-06-24" @default.
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- W2379985474 date "2014-01-01" @default.
- W2379985474 modified "2023-09-24" @default.
- W2379985474 title "Effects of bisphosphates on reduced mortality risk" @default.
- W2379985474 hasPublicationYear "2014" @default.
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