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- W2379988052 abstract "Objective To analyze the clinical features of cryptococcal meningitis and improve the management of such infections.Methods The clinical data of 25 cases of cryptococcal meningitis were analyzed retrospectively.Results The analysis included 17 males and 8 females.Most patients were young adults.Underlying diseases were identified in 21 patients,including AIDS,lymphoma,Sjogren syndrome and myasthenia gravis.All patients had fever and intracranial hypertension.The symptoms included consciousness disorder(17,68%),convulsion(5,20%),impaired vision(9,36%) and hearing loss(6,24%).Meningeal irritation sign was positive in 14 cases.The pathological sign was positive in 12 cases.The level of protein was high and leukocyte count was below 100×106/L in cerebrospinal fluid.Chloride and glucose were lower than normal.The pressure of cerebrospinal fluid was much higher.Cryptococcus neoformans was identified in 23 cases by China ink staining.Antifungal therapy resulted in clinical cure or improvement in 16 cases.Nine patients died.Conclusions Cryptococcal meningitis is severe infection of central nervous system.Cryptococcal meningitis can be confirmed by identifying Cryptococcus in cerebrospinal fluid.Early diagnosis and timely treatment is the key to treatment success." @default.
- W2379988052 created "2016-06-24" @default.
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- W2379988052 date "2010-01-01" @default.
- W2379988052 modified "2023-09-28" @default.
- W2379988052 title "Clinical features of 25 cases of cryptococcal meningitis" @default.
- W2379988052 hasPublicationYear "2010" @default.
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