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- W2379989078 abstract "Objective To investigate the relationship between expression of Seprase and the clinicopathologic characteristics in colorectal cancer. Methods The expression of Seprase in 50 cases of colorectal cancer was detected with immunohistochemistry, Western-blotting technique and semi-quantitative immunohistochemistry, and the relationship between the expression of Seprase and the clinicopathologic characteristics (age, gender, tumor location, tumor size, gross appearance, depth of infiltration, histological classification, lymph node metastasis, venous infiltration, Dukes stage, distant metastasis) was analyzed. Results The expression of Seprase was found both in tumor cells and adjacent stromal cells. The level of Seprase protein was higher in cancer tissue than that in normal tissue, and a semi-quantitative assessment of the immunohistochemistry revealed a significant correlation between Seprase expression and the Dukes stage and the lymph node metastasis. Conclusion The abundant expression of Seprase in colorectal cancer tissue is associated with the Dukes stage and the lymph node metastasis." @default.
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- W2379989078 date "2006-01-01" @default.
- W2379989078 modified "2023-09-27" @default.
- W2379989078 title "Relationship Between Expression of Seprase and Clinicopathologic Characteristics in Colorectal Cancer" @default.
- W2379989078 hasPublicationYear "2006" @default.
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