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- W2380052968 abstract "Objective To inves tigate the effect of systemic glucocorticoid on the large and small airway function in asthma patients.?Methods The treatment group of 30 asth ma patients were given dexamethasone for 2 weeks; while the control group were o rdered the drug for only 3 days as a symptomatic treatment. The other treatments , including inhaling glucocorticoid therapies, were the same in the 2 groups. Th e respiratory function, in terms of FEV 1 (%) and FEF 75 (%), was determi ned before and 3 d, 14 d and 1 year after the treatment.?Results 14 d after treatment, FEV 1 (%) was 13.4% higher in treatment group th an in control group ( t =4.1898, P 0.01), the difference was still obvio us 1 year after treatment ( t =4.2708, P 0.01). When compared with that in the control group, the FEF 75 (%) in treatment group was 74.2% ( t =7.6 075, P 0.01) and 64 7% ( t =6.7884, P 0.01) higher, 14 d and 1 year after treatment, respectively.?Conclusions Prolonged use of systemic glucocorticoid in addition to inhalation of local therapies could i mprove small airway function and prevent airway remodeling effectively in asthma patients." @default.
- W2380052968 created "2016-06-24" @default.
- W2380052968 creator A5075131710 @default.
- W2380052968 date "2003-01-01" @default.
- W2380052968 modified "2023-09-28" @default.
- W2380052968 title "Effect of systemic glucocorticoid on small airway function in asthma patients" @default.
- W2380052968 hasPublicationYear "2003" @default.
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