Matches in SemOpenAlex for { <https://semopenalex.org/work/W2380138143> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2380138143 abstract "Objective To observe the effectiveness of RU486 in the treatment of OHSS model rat. Methods A total of 30 immature female rats aged 22 days were injected s.c. daily with 10 IU pregnant mare serum gonadotropin (PMSG) for 4 consecutive days from the 22 nd to 25 th day of life. On the 26 th day of life, 100 IU human chorionic gonadotropin (HCG) were injected s.c. to produce OHSS model. On the 27 th day of life, 30 rats were randomly divided into five groups. Each group contained 6 rats. The rats in groupⅠ as control group were not given Ru486 treatment; in group Ⅱ to group Ⅴ were given s.c. with the dosage of RU486 1 mg/kg, 5 mg/kg, 10 mg/kg, 20 mg/kg respectively. Fourty-eight hours after RU486 treatment, the ovarian weight, peritoneal capillary permeability and ascites score of all rats were determined. Results The ovarian weight in group Ⅲ and Ⅳ was 0.321 ± 0.027 g, 0.302 ± 0.035 g, respectively, which were significantly lower than that of control group (0.352 ± 0.022 g) (P0.05, P0.05 respectively), peritoneal EB content in group Ⅲ and group Ⅳ was 1.18 ± 0.66 μg and 1.17 ± 0.47 μg, respectively, which were significantly lower than that of control group (2.33 ± 1.06 μg) (P0.001, P0.001 respectively),and the ascites score in group Ⅲ and group Ⅳ was 2.08 ± 0.38, 1.67 ± 0.48, which were significantly lower than that of control group (2.67 ± 0.41) (P0.05, P0.01 respectively). However, there was no significant difference to be found between group Ⅱ and Ⅴ and control group. Conclusion Optimal dosage of RU486 treatment could improve the condition of OHSS in the rat model." @default.
- W2380138143 created "2016-06-24" @default.
- W2380138143 creator A5062400655 @default.
- W2380138143 date "2005-01-01" @default.
- W2380138143 modified "2023-09-24" @default.
- W2380138143 title "Preliminary Study on Effectiveness of RU486 in the Treatment of OHSS Model Rat" @default.
- W2380138143 hasPublicationYear "2005" @default.
- W2380138143 type Work @default.
- W2380138143 sameAs 2380138143 @default.
- W2380138143 citedByCount "0" @default.
- W2380138143 crossrefType "journal-article" @default.
- W2380138143 hasAuthorship W2380138143A5062400655 @default.
- W2380138143 hasConcept C126322002 @default.
- W2380138143 hasConcept C134018914 @default.
- W2380138143 hasConcept C140793950 @default.
- W2380138143 hasConcept C16685009 @default.
- W2380138143 hasConcept C2778782382 @default.
- W2380138143 hasConcept C2780496750 @default.
- W2380138143 hasConcept C29456083 @default.
- W2380138143 hasConcept C71315377 @default.
- W2380138143 hasConcept C71924100 @default.
- W2380138143 hasConcept C86803240 @default.
- W2380138143 hasConceptScore W2380138143C126322002 @default.
- W2380138143 hasConceptScore W2380138143C134018914 @default.
- W2380138143 hasConceptScore W2380138143C140793950 @default.
- W2380138143 hasConceptScore W2380138143C16685009 @default.
- W2380138143 hasConceptScore W2380138143C2778782382 @default.
- W2380138143 hasConceptScore W2380138143C2780496750 @default.
- W2380138143 hasConceptScore W2380138143C29456083 @default.
- W2380138143 hasConceptScore W2380138143C71315377 @default.
- W2380138143 hasConceptScore W2380138143C71924100 @default.
- W2380138143 hasConceptScore W2380138143C86803240 @default.
- W2380138143 hasLocation W23801381431 @default.
- W2380138143 hasOpenAccess W2380138143 @default.
- W2380138143 hasPrimaryLocation W23801381431 @default.
- W2380138143 hasRelatedWork W2080977875 @default.
- W2380138143 hasRelatedWork W2136460167 @default.
- W2380138143 hasRelatedWork W2347633888 @default.
- W2380138143 hasRelatedWork W2350788618 @default.
- W2380138143 hasRelatedWork W2355514207 @default.
- W2380138143 hasRelatedWork W2356323908 @default.
- W2380138143 hasRelatedWork W2360756809 @default.
- W2380138143 hasRelatedWork W2367970870 @default.
- W2380138143 hasRelatedWork W2372505304 @default.
- W2380138143 hasRelatedWork W2374970498 @default.
- W2380138143 hasRelatedWork W2380423562 @default.
- W2380138143 hasRelatedWork W2382656025 @default.
- W2380138143 hasRelatedWork W2387624799 @default.
- W2380138143 hasRelatedWork W2388079283 @default.
- W2380138143 hasRelatedWork W2388360743 @default.
- W2380138143 hasRelatedWork W2391631918 @default.
- W2380138143 hasRelatedWork W2427763101 @default.
- W2380138143 hasRelatedWork W2917198595 @default.
- W2380138143 hasRelatedWork W2992474516 @default.
- W2380138143 hasRelatedWork W833441343 @default.
- W2380138143 isParatext "false" @default.
- W2380138143 isRetracted "false" @default.
- W2380138143 magId "2380138143" @default.
- W2380138143 workType "article" @default.