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- W2380145669 abstract "Aim To study the effect of total saponin of Aralia taibaiensis (SAT) on glycemia, lipid and antioxidation in hyperglycemic mice induced by Alloxan.Methods Alloxan-induced diabetic mice were fed with SAT at the dose of 30,60,120mg·kg-1 respectively for 4 wk. The blood glucose levels, the blood lipid levels and antioxidation levels were assayed after the last feeding.Results After being treated with SAT for 4 weeks, SAT at the dose of 60,120mg·kg-1 significantly lowered the fasting blood glucose compared with normal group (P0.01), and the hypoglycemic effect of SAT reached the peak at the dose of 120mg·kg-1.The levels of TC, TG, FFA and MDA were lower than those of the model control (P 0.05 or P0.01). Ins, HDL-c, SOD activity and ISI increased significantly (P0.05 or P0.01), while LDL-c changed little (P0.05).Conclusion SAT has obvious glucose-lowering effect on hyperglycemic mice.The mechanism may be related to improving the antioxidation level, restoring the blood lipid levels, increasing ISI and improving the insulin resistance in hyperglycemic mice." @default.
- W2380145669 created "2016-06-24" @default.
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- W2380145669 date "2008-01-01" @default.
- W2380145669 modified "2023-09-25" @default.
- W2380145669 title "The Effect of Total Saponin of Aralia Taibaiensis on Glycemia Lipid and Antioxidation in Hyperglycemic Mice" @default.
- W2380145669 hasPublicationYear "2008" @default.
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