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- W2380212409 abstract "Purpose To investigate the possibility of resisting early pregnance when the endometrosis of pseudo-pregnancy mice vivo-transfected by integrin-β3 ASODN. Methods Integrin-β3 was infused to the endometriosis of 1 day pseudo-pregnancy mice, at the same time,the fertilized eggs were implanted to the homolateral duct. The mice were bred normally. Five days later, the expression of integrin-β3 albumen in the endometriosis was detected and the natality of filizl generation was estimated after 19 days. Results There was strong expression of integrin-β3 in mice's endometriosis detected by Western blotting. When pseudopregnancy mice transfected by 10 pmol integrin-β3 ASODN, the expression of integrin-β3 in the indometriosis was weakened meanwhile no expression when 100 pmol did. Simple lipin didn't affect the expression. The natality of filial generation was estimated 19 days later. The inhibition rate of filial generation was 85 % when transfected by integrin-β3 ASODN. Conclusions Integrin-β3 ASODN could be integrated to the endometriosis of pseudo-pregnancy mice, and inhibited the expression of its albumen, then prevent the embryo's implantation." @default.
- W2380212409 created "2016-06-24" @default.
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- W2380212409 date "2005-01-01" @default.
- W2380212409 modified "2023-09-23" @default.
- W2380212409 title "The Effect of Integrin-β3 Antisense Oligonucletied Resisting to the Mice Pregnance" @default.
- W2380212409 hasPublicationYear "2005" @default.
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