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- W2380226646 abstract "Objective To compare the effects of three antiglaucomatous agents on ocular hypertension after pars plana vitrectomy (PPV). Methods One hundred and seventy-five patients aged 18 to 65 years,diagnosed with ocular hypertension after pars plana vitrectomy (PPV),whose baseline intraocular pressure (IOP) prior to and after surgery was (16.62±3.40)mmHg and (30.76±7.47)mmHg,were selected for this experiment. They were divided into 4 groups and each was supplied with 1 or 2 types of antiglaucomatous eye drops. Fifty-six patients in group 1 were treated with a beta-blocker as monotherapy; 36 patients in group 2 were treated with an alpha-adrenergic agonist as monotherapy; 48 patients in group 3 were treated with a beta-blocker in conjunction with a carbonic anhydrase inhibitor (CAI); 35 patients in group 4 were treated with an alpha-agonist,also in conjunction with CAI. All patients were monitored for a decrease in IOP after using eye drops for 3 days and 9 days. Results After using the eye drops for 3 days,the extent of the IOP decrease for group 1 was (9.87±5.16)mmHg; for group 2 was (7.87±6.00)mmHg,for group 3 was (13.03±8.43)mmHg and for group 4 was (9.48±6.42)mmHg. After using the eye drops for 9 days,the extent of the IOP decrease for group 1 was (13.16± 5.09)mmHg,for group 2 was (10.61±6.16)mmHg,for group 3 was (16.60±8.93)mmHg and for group 4 was (13.63±7.96)mmHg. For all 4 groups,the effect on IOP was highly significant after using eye drops for 3 days and 9 days (P0.01). Conclusion For decreasing ocular hypertension after PPV,when either a beta-blocker or alpha-agonist is used as monotherapy,there is very little difference in their effects. However,when either is used as adjunctive therapy in conjunction with CAI,the effect of a beta-blocker is better than an alpha-agonist alone. Furthermore,the effect of a beta-blocker in conjunction with CAI is not only better than a beta-blocker alone as monotherapy,but is also significantly better than an alpha-agonist alone as monotherapy." @default.
- W2380226646 created "2016-06-24" @default.
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- W2380226646 date "2009-01-01" @default.
- W2380226646 modified "2023-09-24" @default.
- W2380226646 title "Clinical research on the medical treatment of ocular hypertension after pars plana vitrectomy" @default.
- W2380226646 hasPublicationYear "2009" @default.
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