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- W2380262790 abstract "Objective To determine whether or not 810 nm low power Ga-Al-As laser treatment can stimulate the regeneration of damaged optic nerves by measuring the expression of brain derive neurotrophic factor(BDNF). Methods Forty-four Wistar rats weighing 180-220 g were randomly divided into the laser therapy group,injury group and normal group,which consist of 20,16 and 8 rats respectively.Each group was subdivided into the 1st,3rd,6th and 9th week subgroups.Standardized crushing of optic nerves was applied to make the model.Then the rats in the laser therapy group were given 60 mW laser of a spot diameter of 5mm on the injured optic nerve for 3 minutes every day.The injury and normal groups received the same treatment with no laser output.The expression of BDNFmRNA was detected with RT-PCR respectively after 1,3,6 and 9 weeks of treatment. Results After the optic nerve was injured,the expression of BDNFmRNA reached the peak one week after the injury and then dropped.At the 1st,3rd,6th and 9th week after the injury,the expression of BDNFmRNA in the laser therapy group was significantly higher than that in the injury group. Conclusions 810 nm low power Ga-Al-As laser can promote the BDNFmRNA expression of rats with optic nerve injury and repair axonal regeneration of neural." @default.
- W2380262790 created "2016-06-24" @default.
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- W2380262790 date "2012-01-01" @default.
- W2380262790 modified "2023-09-23" @default.
- W2380262790 title "The Effect of 810 nm Low Level Semiconductor Laser on the Expression of Brain Derive Neurotrophic Factor in the Retina after Optic Nerve Injury" @default.
- W2380262790 hasPublicationYear "2012" @default.
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