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- W2380268891 abstract "Objective:To investigate the expression of p120(p120ctn) catenin and VEGF in pancreatic carcinoma cell lines, and the relationship between the expression of p120ctn and the biological behaviour of the cell lines. Methods:The expression of p120ctn and VEGF in five pancreatic carcinoma cell lines and normal pancreatic cell(PSCs) were detected by RT-PCR and Western blotting analysis; selected panc-1 and Patu8988 which have visible differential expression of p120ctn and VEGF to detect the biological behaviour using transwell test. Results:In comparison with PSCs, p120ctn were overexpressed in pancreatic carcinoma cell lines; moreover, it had different expression in different cell lines. In the same cell lines,the expression level of p120ctn were correlated with VEGF. There had inverse correlation of p120ctn's expression with the invasion and migration of pancreatic carcinoma. Conclusion:Expression of p120ctn is increased in the pancreatic carcinoma cell lines and correlated with expression of VEGF. Overexpression of p120ctn may play a role in invasion and migration capability of pancreatic carcinoma." @default.
- W2380268891 created "2016-06-24" @default.
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- W2380268891 date "2009-01-01" @default.
- W2380268891 modified "2023-09-27" @default.
- W2380268891 title "The expression and significance of p120 catenin in pancreatic carcinoma cell lines" @default.
- W2380268891 hasPublicationYear "2009" @default.
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