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- W2380332079 abstract "AIM:To investigate the effect and mechanism of Magnolia grandifore oil on lipid metabolism in hyperlipoidemic rat.METHODS:On the basis of establishing hyperlipo-idemic rat model,blood lipids,antioxidative capacity and inflammatory factor were investigated in 50 rats fed on fatty emulsion for 30 days.RESULTS:Magnolia grandifore oil significantly reduced the levels of TC,TG,LDL-C,and increased the level of HDL-C,improved the activity of paraoxonase 1(PON-1).Magnolia grandifore oil was shown to decrease MDA content in serum,and increase the activities of SOD and GSH-Px in serum.Pathological examination showed that Magnolia grandifore oil attenuated hepatic cell steatosis and atherogenesis in aorta wall.CONCLUSION:Magnolia grandifore oil could remarkably modulate the lipid metabolic disorder in hyperlipoidemic rats,and could reduce the occurrence of atherosclerosis and hepatic adipose infiltration.The mechanism of regulating lipid metabolism might be related with the increase in activity of PON-1 and antioxidative capacity,and inhibition of the release of inflammatory factor." @default.
- W2380332079 created "2016-06-24" @default.
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- W2380332079 date "2010-01-01" @default.
- W2380332079 modified "2023-09-24" @default.
- W2380332079 title "Effect of Magnolia grandifore oil on lipid metabolism in hyperlipoidemic rat" @default.
- W2380332079 hasPublicationYear "2010" @default.
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