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- W2380341418 abstract "Objective To evaluate clinical and bacterial efficacy of moxifloxacin for patients with biliary tract disease undergoing operation.Methods A total of 52 patients undergoing operation for biliary tract disease were selected between June and October,2008.Fifty-two patients were randomized,including 32 subjects in the moxifloxacin group and 20 subjects in the control group,i.e.cefoperazone/sulbactam group.Pathogenicbacteria and drug sensitivity were determined in intraoperative bile.Clinical efficacy was observed.Results A case of 48 bacterial isolates were obtained in the bile from 41 patients.The Bile of eleven patients was sterile.The positive rate was 78.8%(41/52) in the bacterial culture of bile.There was no significant difference between the two groups in drug sensitivity(P0.05) and effective percentage to clinical efficacy(66.7% vs 88.2%,P0.05).Chest distress and polypnea occurred in one patient from moxifloxacin group.Conclusion These findings suggest that moxifloxacin is an effective antibiotic of choice for patients undergoing operation for biliary tract disease." @default.
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- W2380341418 date "2012-01-01" @default.
- W2380341418 modified "2023-09-28" @default.
- W2380341418 title "Prospective analysis of application of moxifloxacin in biliary tract disease undergoing operation" @default.
- W2380341418 hasPublicationYear "2012" @default.
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