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- W2380363755 abstract "Objective:To investigate the value of immunohistochemistry detection in diagnosis and treatment of breast cancer patients.Methods:68 cases of breast cancer patients admitted in our hospital between Jan.2011 and Jan.2013 and diagnosed by hollow needle biopsy and pathological diagnosis were selected randomly for our study.All of the patients received immunohistochemistry detection of ER,PR,P53 and Bc1-2.After 3 months' surgical treatment using CEF chemotherapy treatment,SP method of immunohistochemistry detection was used to detect the positive rate of breast cancer patients before and after the CEF chemotherapy treatment on the indexes above.Results:ER and PR had no significant difference before and after CEF chemotherapy treatment,but the comparison of P53 and Bc1-2 showed significant difference(P0.05).The positive and negtive expression of ER and PR and chemotherapy efficacy had no significant difference,but the positive and negtive expression of P53 and Bc1-2 and the efficacy of CEF chemotherapy treatment showed significant difference(P0.05),which was statistically significant.Conclusion:ER and PR detection in immunohistochemistry detection had no significant difference before and after the treatment of breast cancer patients.CEF chemotherapy treatment can inhibit breast cancer growth by inhibiting of P53 and can adjust the tumor cell diifferentiation by increasing the expression of Bcl-2." @default.
- W2380363755 created "2016-06-24" @default.
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- W2380363755 date "2013-01-01" @default.
- W2380363755 modified "2023-09-23" @default.
- W2380363755 title "The Analysis of Breast Cancer Immunohistochemistry Detection in Diagnosis and Treatment of Breast Cancer Patients" @default.
- W2380363755 hasPublicationYear "2013" @default.
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