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- W2380388717 abstract "The GC method was established under the following conditions for the separationand quantitative determination of muscone in plasma: high purity N_2 as the carrier gas, OV-1crosslinked methylsilicone column as the capillary column, FID as the detector, n-Nonadecane as theinternal standard. A linear calibration curve was obtatined by plotting concentration vs peak area ratio,and the linear relatiohship was fine in the range of 1.25 mg/l plasma (r=0.9999). The average re-covery was 98.5±4.8%. The minimum detectable quantity of muscone was 0.8ng/2μl (squivalentto 50 μg/l plasa). The method is simple,sensitive,specific, reproduceable and suitable for the pharma-cokinetic study of muscone. With regard to oral administration in the dosage of 80 mg/kg to rats, theT1/2Ka was 22.0 min,t_(max) was 74.4min,C_(max)was 1.44mg/l, t1/2β was 196.1min demonstrating thatthe absorption and elimination of muscone after p. o. administration were rapid." @default.
- W2380388717 created "2016-06-24" @default.
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- W2380388717 date "1992-01-01" @default.
- W2380388717 modified "2023-09-26" @default.
- W2380388717 title "STUDY ON QUANTITATIVE IN DETERMINATION OF MUSCONE IN PLASMA BY GAS CHROMATOGRAPHY" @default.
- W2380388717 hasPublicationYear "1992" @default.
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