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- W2380400163 abstract "Objective The chromatographic separation of phellodendrine and magnoflorine was established,and the mechanism of ionic liquid in the process was studied by investigating influencing factors. Methods Phellodendrine and magnoflorine were isolated by HPLC with 1-butyl-3-methyl imidazole four fluorine boric acid as a mobile phase additive,and mobile phase pH,ionic strength,buffer solution,ionic liquids and column temperature were all studied by investigating the effect of ionic liquid in the process. Results It was shown that the analytes were separated at baseline with a mobile phase containing ionic liquid under 20 mmol·L-1isocratic elution. The retention value,separation and number of theoretical plates varied with the change of mobile phase. Conclusion It is clarified that ionic liquid mainly acts as neutral ion pair in the separation of phellodendrine and magnoflorine." @default.
- W2380400163 created "2016-06-24" @default.
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- W2380400163 date "2014-01-01" @default.
- W2380400163 modified "2023-09-23" @default.
- W2380400163 title "Mechanism of Ionic Liquids as a Mobile Phase Additives on the Separation of Phellodendrine and Magnoflorine by HPLC" @default.
- W2380400163 hasPublicationYear "2014" @default.
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