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- W2380433062 abstract "Objective: To investigate the effect of vagal nerve stimulation on ventricular arrhythmias during acute myocardial ischemia in aged rats.Methods: Male SD rats were randomly assigned into the following groups:(1) Adult group: Myocardial ischemia(MI) group(n=15): ligation of the anterior descending coronary;Myocardial ischemia + Vagal stimulation(MI-VS) group(n=15) and sham operation(SO) group(n=10): without coronary ligation.(2): Aged group: Myocardial ischemia(MI) group(n=15);Myocardial ischemia + Vagal stimulation(MI-VS) group(n=15) and sham operation(SO) group(n=10).Ventricular arrhythmias were monitored by an electrocardiogram.Results:The incidences of VT and VF of the MI group in aged rats increased significantly during the 30-minute ligation compared to those of the MI group in adult rats(P0.05);there were no significantly differences in the incidences of VT and VF between the MI-VS group and the MI group in aged rats(P0.05);however,the irreversible VF of the MI-VS group in aged rats decreased significantly compared to that of the MI group in aged rats(P0.05).Conclusion:The present study showed that the incidence of ischemia-induced ventricular arrhythmias increased markedly in aged rats,and the anti-arrhythmic effect of vagal nerve stimulation decreased significantly in aged rats." @default.
- W2380433062 created "2016-06-24" @default.
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- W2380433062 date "2009-01-01" @default.
- W2380433062 modified "2023-09-26" @default.
- W2380433062 title "Effect of vagal nerve stimulation on ischemia-induced ventricular arrhythmias in aged rats" @default.
- W2380433062 hasPublicationYear "2009" @default.
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