Matches in SemOpenAlex for { <https://semopenalex.org/work/W2380470129> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2380470129 abstract "Wnt/β-catenin signaling pathway is involved in multiple myeloma.In order to evaluate the function of Wnt/β-catenin signaling pathway in the multiple myeloma,13 bone marrow samples from multiple myeloma patients and myeloma cell lines were analysed by micro-array,real-time PCR.Western blot was used to test the expression of β-catenin in these samples,especially in multiple myeloma stem cells.COX2 inhibitor,CAY10404 was used to evaluate the effect of inhibtion Wnt signaling on the myeloma progression both in vitro and in vivo.Results showed that Wnt/β-catenin signaling highly expressed in myeloma cells especially in myeloma stem cells(P0.05) and CAY10404 significantly inhibited proliferation of myeloma cells and tumorgenesis in Nod-Scid mice(P0.05).These findings provide a rationale for Wnt/β-catenin signaling pathway-based therapy in multiple myeloma,especially in multiple myeloma stem cells." @default.
- W2380470129 created "2016-06-24" @default.
- W2380470129 creator A5015102287 @default.
- W2380470129 date "2013-01-01" @default.
- W2380470129 modified "2023-09-24" @default.
- W2380470129 title "Inhibition of CAY10404 on Wnt/β-catenin Signaling Pathway to Eliminate Multiple Myeloma Stem Cells" @default.
- W2380470129 hasPublicationYear "2013" @default.
- W2380470129 type Work @default.
- W2380470129 sameAs 2380470129 @default.
- W2380470129 citedByCount "0" @default.
- W2380470129 crossrefType "journal-article" @default.
- W2380470129 hasAuthorship W2380470129A5015102287 @default.
- W2380470129 hasConcept C104317684 @default.
- W2380470129 hasConcept C137620995 @default.
- W2380470129 hasConcept C182819311 @default.
- W2380470129 hasConcept C203014093 @default.
- W2380470129 hasConcept C2776364478 @default.
- W2380470129 hasConcept C2776415932 @default.
- W2380470129 hasConcept C2777491412 @default.
- W2380470129 hasConcept C2780007613 @default.
- W2380470129 hasConcept C28328180 @default.
- W2380470129 hasConcept C502942594 @default.
- W2380470129 hasConcept C54355233 @default.
- W2380470129 hasConcept C62478195 @default.
- W2380470129 hasConcept C86803240 @default.
- W2380470129 hasConcept C95444343 @default.
- W2380470129 hasConceptScore W2380470129C104317684 @default.
- W2380470129 hasConceptScore W2380470129C137620995 @default.
- W2380470129 hasConceptScore W2380470129C182819311 @default.
- W2380470129 hasConceptScore W2380470129C203014093 @default.
- W2380470129 hasConceptScore W2380470129C2776364478 @default.
- W2380470129 hasConceptScore W2380470129C2776415932 @default.
- W2380470129 hasConceptScore W2380470129C2777491412 @default.
- W2380470129 hasConceptScore W2380470129C2780007613 @default.
- W2380470129 hasConceptScore W2380470129C28328180 @default.
- W2380470129 hasConceptScore W2380470129C502942594 @default.
- W2380470129 hasConceptScore W2380470129C54355233 @default.
- W2380470129 hasConceptScore W2380470129C62478195 @default.
- W2380470129 hasConceptScore W2380470129C86803240 @default.
- W2380470129 hasConceptScore W2380470129C95444343 @default.
- W2380470129 hasLocation W23804701291 @default.
- W2380470129 hasOpenAccess W2380470129 @default.
- W2380470129 hasPrimaryLocation W23804701291 @default.
- W2380470129 hasRelatedWork W1653920538 @default.
- W2380470129 hasRelatedWork W1911578262 @default.
- W2380470129 hasRelatedWork W2080713919 @default.
- W2380470129 hasRelatedWork W2084666520 @default.
- W2380470129 hasRelatedWork W2115548714 @default.
- W2380470129 hasRelatedWork W2207236750 @default.
- W2380470129 hasRelatedWork W2255473431 @default.
- W2380470129 hasRelatedWork W2294465717 @default.
- W2380470129 hasRelatedWork W2295445086 @default.
- W2380470129 hasRelatedWork W2343289517 @default.
- W2380470129 hasRelatedWork W2626027092 @default.
- W2380470129 hasRelatedWork W2733666383 @default.
- W2380470129 hasRelatedWork W2761419040 @default.
- W2380470129 hasRelatedWork W2767684755 @default.
- W2380470129 hasRelatedWork W2910789146 @default.
- W2380470129 hasRelatedWork W2913314801 @default.
- W2380470129 hasRelatedWork W2920881827 @default.
- W2380470129 hasRelatedWork W2924223758 @default.
- W2380470129 hasRelatedWork W3014724537 @default.
- W2380470129 hasRelatedWork W2618270059 @default.
- W2380470129 isParatext "false" @default.
- W2380470129 isRetracted "false" @default.
- W2380470129 magId "2380470129" @default.
- W2380470129 workType "article" @default.