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- W2380492664 abstract "OBJECTIVE To observe the effect of extracts from celery root on carbon tetrachloride induced acute liver injury mice.METHODS Sixty mice were randomly divided into normal control group,model control group,bifendate pills control group,high-dosage group,middle-dosage group and low-dosage group.The mice in the above groups were fed for 7 days.The drug groups were pretreated intragastrically with 10.0,5.0,2.5 g·kg-1 of extracts from celery root.Bifendate pills groups were pretreated intragastrically with 15 mg·kg-1bifendate.Control animals were given the same volumn physiological saline.On the 7th day of feeding,the mice except normal control group were given 10 ml·kg-1 carbon tetrachloride by abdominal cavity injection.The animals were killed 18h after CCl4 administration.The activities of serum ALT and AST,as well as the pathological changes of the liver were determined in all groups.RESULTS The extracts of celery root significantly decreased carbon tetrach loride induced acute hepatic injury with increasing the activities of AST,ALT.CONCLUSION It is revealed that celery root could prevent carbon tetrachloride from inducingacute liver injury." @default.
- W2380492664 created "2016-06-24" @default.
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- W2380492664 date "2008-01-01" @default.
- W2380492664 modified "2023-09-23" @default.
- W2380492664 title "Protective effect of celery root against acute liver injury by CCl_4" @default.
- W2380492664 hasPublicationYear "2008" @default.
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