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- W2380493998 abstract "OBJECTIVE: To evaluate the clinical efficacy of eszopiclone in the treatment of insomnia. METHODS: 70 patients with insomnia were randomly assigned into research group and control group(n=35). 2 groups were given either eszopiclone 3 mg or zolpidem 10 mg before bedtime for 2 weeks. Clinical efficacy was evaluated using sleep dysfunction rating scale(SDRS) and clinical global impression(CGI). RESULTS: The total scores of SDRS were descended after treatment in the 2 groups, there was no significant difference between 2 groups(P0.05). The scores of clinical global impression were increased, there was no significant difference of 2 groups at the different period(P0.05). The most commonly reported adverse events in clinical trials were bitter taste, dizziness and thirst, there was no significant difference between 2 groups(P0.05). CONCLUSION: Eszopiclone has the same clinical efficacy and safety to zolpidem in the treatment of insomnia. The subjective satisfaction of treatment group is higher than control group, and with statistically significance(P0.05)." @default.
- W2380493998 created "2016-06-24" @default.
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- W2380493998 date "2010-01-01" @default.
- W2380493998 modified "2023-09-22" @default.
- W2380493998 title "Clinical Observation of Eszopiclone or Zolpidem in the Treatment of Insomnia" @default.
- W2380493998 hasPublicationYear "2010" @default.
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