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- W2380494882 abstract "Objective To investigate the correlation between serum levels of interleukin- 2( IL- 2) and interleukin- 6( IL- 6) and HCV induced liver cirrhosis and hepatocellular carcinoma( HCC). Methods Thirty- one hepatitis C patients treated in our hospital from October 2012 to October 2013 were randomly selected. The patients were divided into chronic hepatitis C group,hepatitis C cirrhosis group and HCV- related HCC group; 18 healthy subjects were as control. Serum alanine aminotransferase( ALT),total bilirubin( TBIL),IL- 2 and IL- 6 levels were detected and compared. Results Compared with the normal control group,ALT and TBIL levels were significantly increased in all three patient groups,there were significant differences( all P 0. 05),whereas ALT level was significantly lower in HCV- related HCC group than those in chronic hepatitis C group and hepatitis C cirrhosis group,there were significant differences( all P 0. 05). Compared with normal control group,IL- 2 level was significantly decreased,but IL- 6 level was significantly increased in all three patients groups,there were significant differences( all P 0. 05). Along with the progression of the disease,IL- 2 level was gradually decreased whereas IL- 6 level was gradually increased in chronic hepatitis C group,hepatitis C cirrhosis group and HCV- related HCC group. Conclusion Changes of serum IL- 2 and IL-6 levels are associated with the development of HCV C cirrhosis and HCV- related HCC." @default.
- W2380494882 created "2016-06-24" @default.
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- W2380494882 date "2015-01-01" @default.
- W2380494882 modified "2023-09-24" @default.
- W2380494882 title "Correlation between changes of serum IL-2 and IL-6 levels and HCV induced liver cirrhosis and cancer" @default.
- W2380494882 hasPublicationYear "2015" @default.
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