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- W2380496318 abstract "Objective:To quantitatively analyze the enhancement characteristics of pancreatic insulinoma in different phases and to study the value of multi-row detector CT(MDCT) in the diagnosis before surgery.Methods:The CT materials of 38 patients with surgery and pathology proven insulinoma were reviewed.The morphology,enhanced pattern in various phases,degree of enhancement as well as the sensitivity for tumor localization and potential causes of false negative diagnosis were retrospectively analyzed.Results:The sensitivity for the preoperative diagnosis of insulinoma was 81.6% with dynamic enhanced dual-phase MDCT.The sensitivity was 81.6% in the arterial phase and 60.5% in the portal-venous phase with significant statistical difference(P=0.043).The mean attenuation values of the insulinoma and the surrounding tumor-free normal pancreatic parenchyma on the unenhanced images were(40.32±8.13)HU and(44.48±6.75)HU respectively,with significant statistical difference(P0.001).Of the 36 tumors,obvious enhancement could be showed on at least one phase after contrast administration.The mean CT attenuation values of the insulinoma and the surrounding normal pancreatic parenchyma on arterial phase was(113.66±27.26)HU and(80.5±15.43)HU respectively,with significant statistical difference(P0.001).The mean attenuation values of the insulinoma and the normal pancreatic parenchyma on the portal phase was(111.59±19.05)HU and(90.5±13.91)HU respectively,with significant statistical difference as well(P0.001).The attenuation of insulinoma in the arterial phase and the portal venous phase was(73.44±29.23)HU and(71.22±21.64)HU respectively,with no significant statistical difference(P=0.627).The tumor to normal pancreas attenuation difference in the arterial phase and portal venous was(33.16±20.64)HU and(20.09±16.31)HU respectively,with significant statistical difference(P=0.006).In the seven cases missed by CT,five tumors were isodense in every phase and two were ectopic insulinoma.Conclusion:Dual-phase dynamic enhanced thin thickness MDCT has a promising sensitivity in the detection of pancreatic insulinoma.Arterial phase after contrast enhancement was significantly helpful for the diagnosis." @default.
- W2380496318 created "2016-06-24" @default.
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- W2380496318 date "2009-01-01" @default.
- W2380496318 modified "2023-09-23" @default.
- W2380496318 title "Value of Dual-phase Thin Thickness Dynamic Enhanced Muti-row Detector CT in the Preoperative Diagnosis of Pancreatic Insulinoma" @default.
- W2380496318 hasPublicationYear "2009" @default.
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