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- W2380510195 abstract "Objective:To investigate the change of T cell subtypes in mesenteric lymph node(MLN) of C57BL/6 mice infected by Sj for 46 weeks.Methods:C57BL/6 mice were infected with Sj cercariea by applying abdomen walls.The numbers of MLN lymphocytes were counted after 4-6 weeks.Subtypes of T cells which secreted different cytokines were detected by flow cytometry.Results:The number of MLN lymphocytes in infected mice increased obviously.IFN-γ producing Th1 cells increased by 1 fold.IL-4 and IL-5 secreting Th2 cells increased by nearly 20 folds.The axis of Th1/Th2 shifted.In addition,IL-17 secreting Th17 cells were increased dramatically.Conclusion:The MLN of C57BL/6 mice infected with Sj has stored more lymphocytes,which polarizes to Th2 and Th17 phenotyoes." @default.
- W2380510195 created "2016-06-24" @default.
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- W2380510195 date "2011-01-01" @default.
- W2380510195 modified "2023-09-25" @default.
- W2380510195 title "The alteration of T cell subtype in mesenteric lymph node (MLN) in mice infected by Schistosome japonicum" @default.
- W2380510195 hasPublicationYear "2011" @default.
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