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- W2380517327 abstract "Objective To evaluate the efficacy and tolerability of venlafaxine extended release(XR) and paroxetine for patients with generalized anxiety disorder(GAD).Methods Twenty-five patients who met DSM-IV criteria for GAD were randomly assigned to venlafaxine XR and another 23 patients to paroxetine and the treatment lasted 8 weeks.Efficacy was assessed with the Hamilton Rating Scale for Anxiety(HAMA) and Clinical Global Impression of Illness(CGI-SI) scale.Safety was evaluated by TESS,laboratory and physical examination throughout the study.Results The scores showed a significant decrease over time in both groups.Effects of both groups were similar.There were no serious adverse events in both groups.Conclusion Either venlafaxine XR or paroxetine would be effective and tolerable for patients with GAD." @default.
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- W2380517327 date "2009-01-01" @default.
- W2380517327 modified "2023-09-24" @default.
- W2380517327 title "Controlled study of generalized anxiety disorder with venlafaxine extended release and paroxetine" @default.
- W2380517327 hasPublicationYear "2009" @default.
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