Matches in SemOpenAlex for { <https://semopenalex.org/work/W2380522056> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2380522056 abstract "Objective To define the effects of high blo od pressure upon coronary flow reserve (CFR) measured by myocardial contrast echocardiography (MCE). Methods Studies were performed in 9 closed chest swine. Low-energy, real-time MCE was performed with commercial instruments in short axis view at papillary muscle level while infusing BR1 (Sonovue, Bracco) at 0.5 ml/min. High-energy FLASH frames destroyed bubbles every 15 cardiac cycles, and resultant time-intensity curves derived from these sequences were fitted to an exponential function as y = A(1-e -bt )+c from which the rate of signal rise (b) was obtained. CFR was calculated as the ratio of b values prior to and after adenosine infusion, and was obtained before and after increasing blood presure with vein infusion phenylephrine. CFR was independently determined by fluorescent microspheres.Results Phenylephrine increased the mean blood presure from 129/107 mm Hg(1 mm Hg=0.133 kPa) to 196/153 mm Hg (P 0.001 ) and changed heart rate from 114 beats/min to 124 beats/min (P 0.05 ). Adenosine produced a similar increase of CFR: 2.5 vs 3.1 for MCE and microspheres respectively. Blood presure elevation post phenylephrine increased resting and decreased post adenosine values of b ( 0.7 and 0.9 respectively) with a marked reduction in CFR ( 1.5 , P 0.05 ). CFR was also decreased as measured by microspheres ( 1.8 ). Conclusions Phenylepherine induced hypertension reduces quantitative parameters of CFR, derived from destroy/refill sequences by MCE." @default.
- W2380522056 created "2016-06-24" @default.
- W2380522056 creator A5023732082 @default.
- W2380522056 date "2003-01-01" @default.
- W2380522056 modified "2023-09-26" @default.
- W2380522056 title "Effects of variable blood pressure upon coronary flow reserve determined by myocardial contrast echocardiography" @default.
- W2380522056 hasPublicationYear "2003" @default.
- W2380522056 type Work @default.
- W2380522056 sameAs 2380522056 @default.
- W2380522056 citedByCount "0" @default.
- W2380522056 crossrefType "journal-article" @default.
- W2380522056 hasAuthorship W2380522056A5023732082 @default.
- W2380522056 hasConcept C126322002 @default.
- W2380522056 hasConcept C127413603 @default.
- W2380522056 hasConcept C158846371 @default.
- W2380522056 hasConcept C164705383 @default.
- W2380522056 hasConcept C178853913 @default.
- W2380522056 hasConcept C189942447 @default.
- W2380522056 hasConcept C2776157398 @default.
- W2380522056 hasConcept C2776991684 @default.
- W2380522056 hasConcept C2777952589 @default.
- W2380522056 hasConcept C2777953023 @default.
- W2380522056 hasConcept C2778707443 @default.
- W2380522056 hasConcept C2989005 @default.
- W2380522056 hasConcept C42219234 @default.
- W2380522056 hasConcept C42360764 @default.
- W2380522056 hasConcept C71924100 @default.
- W2380522056 hasConcept C84393581 @default.
- W2380522056 hasConceptScore W2380522056C126322002 @default.
- W2380522056 hasConceptScore W2380522056C127413603 @default.
- W2380522056 hasConceptScore W2380522056C158846371 @default.
- W2380522056 hasConceptScore W2380522056C164705383 @default.
- W2380522056 hasConceptScore W2380522056C178853913 @default.
- W2380522056 hasConceptScore W2380522056C189942447 @default.
- W2380522056 hasConceptScore W2380522056C2776157398 @default.
- W2380522056 hasConceptScore W2380522056C2776991684 @default.
- W2380522056 hasConceptScore W2380522056C2777952589 @default.
- W2380522056 hasConceptScore W2380522056C2777953023 @default.
- W2380522056 hasConceptScore W2380522056C2778707443 @default.
- W2380522056 hasConceptScore W2380522056C2989005 @default.
- W2380522056 hasConceptScore W2380522056C42219234 @default.
- W2380522056 hasConceptScore W2380522056C42360764 @default.
- W2380522056 hasConceptScore W2380522056C71924100 @default.
- W2380522056 hasConceptScore W2380522056C84393581 @default.
- W2380522056 hasLocation W23805220561 @default.
- W2380522056 hasOpenAccess W2380522056 @default.
- W2380522056 hasPrimaryLocation W23805220561 @default.
- W2380522056 hasRelatedWork W1977716709 @default.
- W2380522056 hasRelatedWork W2041853154 @default.
- W2380522056 hasRelatedWork W2053282098 @default.
- W2380522056 hasRelatedWork W2074669831 @default.
- W2380522056 hasRelatedWork W2080011884 @default.
- W2380522056 hasRelatedWork W2080775664 @default.
- W2380522056 hasRelatedWork W2089161547 @default.
- W2380522056 hasRelatedWork W2127732642 @default.
- W2380522056 hasRelatedWork W2232983009 @default.
- W2380522056 hasRelatedWork W2233087823 @default.
- W2380522056 hasRelatedWork W2349529059 @default.
- W2380522056 hasRelatedWork W2395871932 @default.
- W2380522056 hasRelatedWork W2405750689 @default.
- W2380522056 hasRelatedWork W2405927358 @default.
- W2380522056 hasRelatedWork W2417255809 @default.
- W2380522056 hasRelatedWork W2431437918 @default.
- W2380522056 hasRelatedWork W3140135616 @default.
- W2380522056 hasRelatedWork W3140624369 @default.
- W2380522056 hasRelatedWork W3147305292 @default.
- W2380522056 hasRelatedWork W3031489215 @default.
- W2380522056 isParatext "false" @default.
- W2380522056 isRetracted "false" @default.
- W2380522056 magId "2380522056" @default.
- W2380522056 workType "article" @default.