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- W2380531018 abstract "Objective:To investigate the pharmacological action of Xinnaosu extract(Effective fractions) on acute cerebral ischemia induced by arachidonic acid in rats.Method:The cerebral ischemia model was established by injecting arachidonic acid into the internal carotid artery of rats.The pathologic examination,the amplitude and frequency of electroencephalographic waves,death rate,platelet aggregation rate,thromboxane B2,6-keto-PGF1а,LPO were detected respectively.Result:This product can obviously help the abnormal amplitude and frequency of electroencephalographic waves caused by acute cerebral ischemia recover quickly,reduce the death rate,the maximum agglutination and aggregation rate of platelet.It also can degrade the relative value of TXB2/6-Keto-PGF1a in blood plasma and depress the formation of LPO in blood plasma.Histological examination indicated that,for the group Ⅰrats(dose of Xinnaosu extract),blood vessels in the brain tissue had expanded slightly,scattered foci of microthrombosis were phanerous,cerebral edema was not obvious,none of hemorrhagic focus and angiorrhexis.For the model group Ⅱ rats(the control group),blood vessels in the brain tissue had expanded vigorously.Congestion,edema and a lot of microthrombus and angiorrhexis in the cerebral vessels were seen,distributed all over the brain tissue.Conclusion:Xinnaosu Extract has a good therapeutic effect towards acute cerebral ischemia induced by arachidonic acid in rats." @default.
- W2380531018 created "2016-06-24" @default.
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- W2380531018 date "2010-01-01" @default.
- W2380531018 modified "2023-09-25" @default.
- W2380531018 title "Therapeutic Effects of Xinnaosu Extract on Acute Cerebral Ischemia Induced by Arachidonic Acid in Rats" @default.
- W2380531018 hasPublicationYear "2010" @default.
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