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- W2380557612 abstract "Objective To investigate the effect of glutamate on cultured cerebellar cortical neurons of neonatal rats.Methods The cultured neuron were exposed to glutamate for 10 min, and the lactate dehydrogenase (LDH), superoxide dismutase (SOD), malondialdehyde (MDA) in the media were measured.Results LDH activity, content of MDA and the cell loss in glutamate-treated cell culture were significantly higher than those in the control, however, the SOD activity decreased.Conclusion The results indicate that the glutamate does have neurotoxicity, which may be induced by oxygen free radicals." @default.
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- W2380557612 date "2002-01-01" @default.
- W2380557612 modified "2023-09-28" @default.
- W2380557612 title "Effect of glutamate on cultured rat cortical cells" @default.
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