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- W2380586893 abstract "OBJECTIVE To evaluate the outcome and adverse effects of levamlodipine besylate combined with irbesartan/hydrochlorothiazide in treating elderly hypertension. METHODS Two hundred patients were randomly divided into 3 groups: Group A (60 patients) using levamlodipine besylate (5mg, QN) ; Group B using irbesartan/hydrochlorothiazide (150mg/12.5mg, QM) and Group C using the combination of levamlodipine besylate (5mg, QN) with irbesartan hydrochlorothiazide (150mg/12.5mg, QM). The treatment course was 5 weeks and plasma Apelin-12 level was determined pretreatment and posttreatment. RESULTS Effective rates for Group A, B and C were 51.6%, 73.8% and 82.6%, respectively.Adverse effect rates for Group A, B and C were 18.3%, 20.0% and 18.7%, respectively. Plasma Apelin-12 levels were significantly evaluated after treatment. CONCLUSION The outcome of combination of levamlodipine besylate with irbesartan/hydrochlorothiazide in treating elderly hypertension is satisfactory." @default.
- W2380586893 created "2016-06-24" @default.
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- W2380586893 date "2013-01-01" @default.
- W2380586893 modified "2023-09-24" @default.
- W2380586893 title "Clinical evaluation of levoamlodipine besylate combined with irbesartan and hydrochlorothiazide in treatment of senile hypertension as well as the effects on plasma Apelin-12" @default.
- W2380586893 hasPublicationYear "2013" @default.
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