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- W2380615517 abstract "OBJECTIVE To study the effect of pomegranate flower polyphenol(PFP) on insulin resistance and glycometabolism in DM rats.METHODS Model group was established with high calorie feeding and small dose injection of STZ(45 mg·kg-1).DM rats were randomly assigned to model group,PFP high dose group,PFP low dose group and normal control group.After 4 weeks treatment with PFP,then fasting plasma glucose(FPG)、fasting insulin(Fins)、free fatty acid、IL-6、the activity of hexokinase and malic dehydrogenase(MDH)、muscle glycogen and hepatic glycogen were detected.RESULTS After 4 weeks treatment,FPG、Fins FFA、Il-6 and hepatic MDH activity were reduced.The activity of hexokinase and muscle glycogen increased effectively.No effective influence on hepatic glycogen was discovered.CONCLUSION The results suggested that PFP could be used to reduce FPG,Fins and insulin resistance.The mechanism of action is supposed to be related to the reduction of FFA IL-6 and MDH activity,and the elevation of activity of HK,subsequently induce the elevation of MG." @default.
- W2380615517 created "2016-06-24" @default.
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- W2380615517 date "2011-01-01" @default.
- W2380615517 modified "2023-09-25" @default.
- W2380615517 title "Effects of pomegranate flower polyphenol on glycometabolism of streptozotocin-induced type 2 diabetic rats" @default.
- W2380615517 hasPublicationYear "2011" @default.
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