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- W2380708189 abstract "AIM:To compare the pathological change and survival rate between different intestinal segment grafts in rat models of small bowel transplantation(SBT). METHODS: 320 inbred Wistar rats were divided randomly into 4 groups: group A (control, n=80), group B(heterotopic total SBT, n=80), group C (heterotopic segmental SBT, n=80, the grafts were obtained from middle and distal intestine, the length ranging from 15 cm to 50 cm) and group D (heterotopic segmental SBT, n=80, the grafts were obtained from proximal portion of intestine and the length was 15-50 cm). After operation, conventional fluids and antibiotics were given and the stoma condition was also observed everyday. Glucosylglucose solution was given through the stoma on day 1, 7, 14 and 30 after operation. Twenty rats were randomly chosen from each group on day 7,14,30 after operation and 1ml blood sample was then obtained for analyzing the level of serum glucose (SG) and SG Absorption value. The graft tissue samples were also taken from each group for further pathological analysis. RESULTS: The pathological change was more severe in group B than in group C and D, and the survival rate was also lower. However, the SG Absorption value had no statistically significant difference between different groups. CONCLUSION: Segmental SBT has a better prognosis than total SBT in rat models, and the optimal grafts are intestinal segments 5cm from Treiz ligament and 15-20 cm in length." @default.
- W2380708189 created "2016-06-24" @default.
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- W2380708189 date "2008-01-01" @default.
- W2380708189 modified "2023-09-28" @default.
- W2380708189 title "Selection of graft for small bowel transplantation in rat" @default.
- W2380708189 hasPublicationYear "2008" @default.
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