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- W2380711837 abstract "Objective To determine the prevalence of hepatitis B virus surface antigen( HBs Ag) and antibody to HBs Ag( Anti-HBs),describe the epidemiology of hepatitis B,evaluate the impact of hepatitis B vaccine( Hep B) in the childhood immunization program,and provide evidence for developing further disease control and prevention strategies in Hunan province. Methods A stratified random cluster sampling was conducted using three levels: counties( city or district) were selected at the first level stage,villages( or residential communities) at the second level,and individuals at thethird level. Sample size was determined usingthe formula n = 400 × Q / P,in which P( the prevalence rate of HBs Ag in population of aged1-59 year old) was set as 4%,yielding a desired sample size of 9600. Statistical Analysis System institute software 9. 4 was used to analyze HBs Ag and Anti-HBs prevalence rates. Analyses were conductedusing weightings to account for the complex survey design; Taylor series was used to determine point estimates and their variances. Results The prevalence rates of HBs Ag and Anti-HBs among 1-59 year olds were 7. 23% and 52. 02% respectively,and were 6. 09% and 50. 98% in urban settings,and 8. 33% and 53. 04% in rural settings. The prevalence rates of HBs Ag and Anti-HBs was8. 18% and 51. 37% among males,and 6. 27% and 52. 68% among females. The prevalence rate of HBs Ag amongchildren aged 1-4 and 5-14,and adults 15-59 years old were 0. 82%,1. 71%,and 8. 68%,respectively,while the Anti-HBs rates were 54. 77%,55. 25%,and 51. 25%. Conclusions Hep B vaccine had a clearly positive impact in the childhood immunization program. The prevalence of HBs Ag among children aged 1-4 was less than 1%. However,the current situation for control and prevention of Hep B is still a challenge. The overall prevalence rate of HBs Ag was above 7%,and Hunan province,therefore,is still classified as medium epidemic level." @default.
- W2380711837 created "2016-06-24" @default.
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- W2380711837 date "2015-01-01" @default.
- W2380711837 modified "2023-09-28" @default.
- W2380711837 title "Prevalence of Hepatitis B Virus Surface Antigen(HBsAg) and Antibody to HBsAg among 1-59 Year Olds,Hunan Province" @default.
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