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- W2380733208 abstract "Objective To evaluate the diagnostic value of detecting plasma(1→3)-β-D-glucan(BG) for invasive pulmonary aspergillosis in rats.Methods Pulmonary aspergillosis model was established with immunosuppressive rats.MB-80 Microbiology Kinetic Rapid Reader and GKT-5M Set(G test) were used to detect the plasma contents of BG,and the results were compared with those detected by ELISA(GM test,Platelia Aspergillus).Results ① Nine samples(60.0%) in the immunosuppression infection group had positive results,with the plasma BF level being 10.12—181.50 ng/L [a median of 56.27 ng/L];the rest 6 samples had a negative results.The positive rate of G test in the immnuosuppression infection group was significantly higher than that of the normal control group(0,P0.01).② The sensitivity and specificity of G test for IPA were 60% and 97%,respectively;those of GM test were 73% and 91%,respectively.③ The combination of G test and GM test had a higher sensitivity and specificity in diagnosis of IPA,being 86% and 98%,respectively.Conclusion G test,as a novel non-invasive index for diagnosis of IPA,has high specificity and satisfactory clinical diagnosis value.When combined with GM test,the sensitivity and specificity of G test for diagnosis of IPA are greatly increased.(Shanghai Med J,2009,32: 881-884)" @default.
- W2380733208 created "2016-06-24" @default.
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- W2380733208 date "2009-01-01" @default.
- W2380733208 modified "2023-09-23" @default.
- W2380733208 title "Diagnostic value of detecting (1→3)-β-D-glucan for invasive pulmonary aspergillosis in rats" @default.
- W2380733208 hasPublicationYear "2009" @default.
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