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- W2380771855 abstract "Objective To investigate the variation of tumor necrosis factor-α(TNF-α) and T lymphocyte Subgroup in peripheral blood of the patients with psoriasis vulgaris and their clinical significance.Methods The levels of T lymphocyte subsets in peripheral blood were measured by flow cytometry and TNF-α is detected by ELISA in 50 patients with psoriasis vulgaris and 32 people in control group.Results The percentage of CD4+T cells and the ratio of CD4+/CD8+ from patients with psoriasis vulgaris were significantly lower than that of the control group(P0.01 and P0.05).Comparied with the control group,The sera TNF-α from patients with psoriasis vulgaris were significantly higher(P0.01).Conclusion There is disturbence of immunological function of patients with psoriasis vulgaris.TNF-α is a kind of cytokine closely related to the immune response.Thus,T lymphocyte subgroups and TNF-α play very important roles in the course of psoriasis vulgaris disease." @default.
- W2380771855 created "2016-06-24" @default.
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- W2380771855 date "2010-01-01" @default.
- W2380771855 modified "2023-09-28" @default.
- W2380771855 title "Clinical Significance of Determination of Changes of Serum TNF-α Contents and T-cell Subgroup Distribution Type in Patients with Psoriasis Vulgaris" @default.
- W2380771855 hasPublicationYear "2010" @default.
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