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- W2380777421 abstract "OBJECTIVE:To systematically evaluate the efficacy and safety of colchicine for the prevention and treatment ofpericarditis. METHODS:Retrieved from OVID,EMbase,SCI,CBM,CNKI,VIP,randomized controlled trials(RCTs) of colchi-cine for the prevention and treatment of pericarditis were included. Meta-analysis were carried out for homogeneity study using Rev-Man 5.0 software after systematical study selection,data extraction and quality evaluation. RESULTS:5 RCTs were included,in-volving 795 patients. Meta-analysis indicated the differences of the incidence of the PPS[RR=0.44,95%CI(0.27,0.70) ,P=0.000 6]and the recurrence rate [RR=0.42,95%CI(0.29,0.60) ,P0.000 1] between groups were significant. There was no significant dif-ference in the incidence of ADRs between 2 groups [RR=1.22,95%CI(0.72,2.07) ,P=0.47]. CONCLUSION:Based on routinetreatment or routine treatment combined with aspirin,colchicine is safe and effective in the prevention and treatment of pericarditis." @default.
- W2380777421 created "2016-06-24" @default.
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- W2380777421 date "2012-01-01" @default.
- W2380777421 modified "2023-09-25" @default.
- W2380777421 title "Efficacy and Safety Evaluation of Colchicine for the Prevention and Treatment of Pericarditis:a Systematic Review" @default.
- W2380777421 hasPublicationYear "2012" @default.
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