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- W2380869113 abstract "[Objective] To evaluate the relationship between level of IL-6,IL-8 in sera and the activity of systemic lupus erythematosus(SLE).[Methods] We divided 71 cases with active SLE into two groups(active SLE,non-active SLE),serum level of IL-6,IL-8 were measured by ELISA method.[Result] The serum level of IL-6,IL-8 in SLE patients were respectively(97.3±41.3)pg/mL and(104.4±48.7)pg/ml,significantly higher than normal control:(37.5±8.4)pg/mL and(31.5±10.5)pg/mL(P0.01).Furthermore,the serum level of IL-6,IL-8(108.4±43.2) and(113.5±46.2)pg/mL from active SLE patients were evidently higher than those(71.3±38.7) and(77.4±41.3)pg/mL,from non-active SLE(P0.01).The serum level of cytokines had a positive correlation with the activity of SLE.(r=0.942;r=0.936).[Conclusions] Immunilogical system's function disturbance and abnormality in SLE cause the abnormal increase of cytokines.Supervision of serum cytokines has important clinical value in understanding activity of SLE,instructing clinical therapy,observation of therapy effect and judging the prognosis." @default.
- W2380869113 created "2016-06-24" @default.
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- W2380869113 date "2007-01-01" @default.
- W2380869113 modified "2023-09-23" @default.
- W2380869113 title "Changes in serum level of IL-6,IL-8 in active patiets with systemic lupus erythematosus and its clinic value" @default.
- W2380869113 hasPublicationYear "2007" @default.
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