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- W2380909905 abstract "Objective To investigate the apoptosis of peripheral blood lymphocytes before and after the treatment of Rheumatoid Arthritis(RA) with methotrexate and/or cyclophosphamide.Methods Thirty RA patients received treatment programs of MTX,CTX,and MTX+CTX randomly.Ten healthy subjects were enrolled as controls.The apoptosis of peripheral blood lymphocytes were detected by Flow cytometry.Results The apoptosis ratios of peripheral blood lymphocytes were not significantly different between patients before treatment and controls(P0.05).The apoptosis level of patients who received combination treatment is significantly higher than that of patients who received MTX or CTX alone(P0.05).There was no correlation between the apoptosis ratios and the score of DAS28,ESR and CRP.Conclusion The combination of MTX and CTX can effectively induce the apoptosis of peripheral blood lymphocytes of RA patients." @default.
- W2380909905 created "2016-06-24" @default.
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- W2380909905 date "2008-01-01" @default.
- W2380909905 modified "2023-09-25" @default.
- W2380909905 title "Apoptosis of Peripheral Blood Lymphocytes after Treatment of Rheumatoid Arthritis with Methotrexate and Cyclophosphamide" @default.
- W2380909905 hasPublicationYear "2008" @default.
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