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- W2380917547 abstract "The objective of this study was to investigate the clinicopathologic characteristics and differential diagnosis of low grade endometrial stromal sarcoma.Ten cases of low grade endometrial stromal sarcoma were observed by histologic and immunohistochemical staining.The clinical manifestation of these patients was irregular vaginal bleeding.Microscopically,the tumor was densely cellar and composed of uniform,oval to spindle-shaped cells of endometrial stromal-type,and cellular atypia and pleomorphism were absent.A rich network of delicate small arterioles resembling the spiral arterioles of the late secretory endometrium supported the proliferating cells.Perivascular hyalinization and a stellate or starburst pattern of hyalinization occurred in some cases.Reticulin stains revealed a dense network of fibrils surrounding individual cells or small groups of cells.Immunohistochemically,8 cases were positive for CD10,6 cases for ER,6 cases for PR,2 cases for actin,and all cases were negative for CD34,CD117 and Melan-A.In conclusion,LESS is easily mistaken for other lesions.The differential diagnosis includes endometrial stromal nodule,undifferentiated endometrial sarcoma,cellular leiomyoma,intravenous leiomyomatosis,and perivascular epithelioid cell tumor.Histopathological and immunohistochemical findings are helpful in differential diagnosis." @default.
- W2380917547 created "2016-06-24" @default.
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- W2380917547 date "2010-01-01" @default.
- W2380917547 modified "2023-09-27" @default.
- W2380917547 title "Clinical diagnosis and treatment of low-grade endometrial stromal sarcoma" @default.
- W2380917547 hasPublicationYear "2010" @default.
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