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- W2380932743 abstract "Objective To observe the changes in contents of plasmendothelin-1(ET-1), prostaglandin-E_2(PGE_2), thromboxan B_2(TXB_2) and 6-ketone-prostaglandin F_ 1α(6-Keto-PGF_ 1α) in the model rats of avascular necrosis of the femoral head(ANFH) induced by diabetes . Methods To establish immediate streptozotocin (STZ)-DM model rats using intraperitoneal injection one time with the dose of 60 mg/kg, then determined the levels of plasma ET-1, PGE_2, TXB_2 and 6-Keto-PGF_ 1α of the model rats and observed the pathology of the femoral head. Results It was shown that the levels of plasma ET-1, PGE_2, TXB_2 in the experimental group all remarkably increased, while that of 6-Keto-PGF_ 1α decreased strikingly comparing with the control. Conclusion The factors of plasma ET-1, PGE_2, TXB_2 and the dysequilibrium of T/K ratio involve in the development of microangiopathy in femoral head and elicit of ANFH." @default.
- W2380932743 created "2016-06-24" @default.
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- W2380932743 date "2005-01-01" @default.
- W2380932743 modified "2023-09-23" @default.
- W2380932743 title "Changes in Contents of Plasma ET-1, PGE_2, TXB_2 and 6-Keto-PGF_1α in Diabetes Induced Avascular Necrosis of Femoral Head in Rats" @default.
- W2380932743 hasPublicationYear "2005" @default.
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