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- W2380945900 abstract "Objective To define the histologic range of cerebral ischemic penumbra after focal cerebral ischemia reperfusion in rats. Methods A model of middle cerebral artery occlusion/reperfusion w as established. The ischemic penumbra and central area were distinguished by TTC , Toluidine blue, Nissl and HE staining methods. Results The ischemic area located at lower frontoparietal cortex and lateral striatum 2 h after reperfusion, then increased gradually and peaked on 1-2 d and expanded to the upper frontoparietal cortex, piriform cortex and me dial striatum, and returned to reperfusion of 2 h level on day 7-14. There was a transitional area in which the staining color and the structure of neuron wer e between normal and ischemic area. The number of neuron reduced significantly w ith main characteristics of necrosis in ischemic central area and apoptotic prop erty in ischemic penumbra. Conclusion The ischemic central area located at lower frontoparie tal cortex and lateral striatum, while the ischemic penumbra at upper frontopari etal cortex, medial striatum and piriform cortex." @default.
- W2380945900 created "2016-06-24" @default.
- W2380945900 creator A5062033506 @default.
- W2380945900 date "2003-01-01" @default.
- W2380945900 modified "2023-09-28" @default.
- W2380945900 title "THE DEFINITION OF CEREBRAL ISCHEMI C PENUMBRA AFTER FOCAL CEREBRAL ISCHEMIA REPERFUSION IN RATS" @default.
- W2380945900 hasPublicationYear "2003" @default.
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