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- W2380952594 abstract "OBJECTIVE:To observe protective effects of 3 brands of Compound Danshen Tablets with different quality against hypoxia and myocardial ischemia.METHODS:The technique of TLC was used to identify borneol of the 3 brands of compound Danshen tablets and the HPLC method was used to assay the active components contained in the tablets; pharmacodynamic tests were performed to observe the changes in hypoxia endurance time of mice and indices of myocardial ischemia of rats after administration of Compound Danshen Tables.RESULTS:The 3 brands of compound Danshen Tables could prolong the survival time of normobaric hypoxia in varying degrees; determination of 3 indicators including heart rate,S-T segment and T wave in Wistar rats with pituitrin-induced acute myocardial ischemia revealed that all the 3 brands of compound Danshen Tables had the trend of protecting myocardial tissue and improving myocardial ischemia, with group 1 showing the best improvement, followed by group 2 and 3.CONCLUSION:All the 3 brands of compound Danshen tablets have the pharmacodynamic effects of improving myocardial ischemia,much as in group1,followed by group2 and group 3.The results indicate that the quality difference of Compound Danshen Tablets is associated with pharmacodynamic effect to some degree." @default.
- W2380952594 created "2016-06-24" @default.
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- W2380952594 date "2010-01-01" @default.
- W2380952594 modified "2023-09-25" @default.
- W2380952594 title "Protective Effects of Compound Danshen Tables against Hypoxia and Myocardial Ischemia" @default.
- W2380952594 hasPublicationYear "2010" @default.
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