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- W2380973722 abstract "75 patients underwent surgical operations under epidural anesthesia were administered drug via the epidural catheter when they reported post-operative pain after the disap pearance of the anesthetic effect. The patients were randomly distributed into 3 groups and administered with 3 different solutions in a blind manner. Solution A: ketamine 25mg+ bupivacaine 0. 75% (2ml) and made up to 10 ml by normal saline. Solution B: Ketamine 25 mg in 10 ml normal saline. Solution C: bupivacaine 0. 75% 2 ml, in 10 ml normal saline. The patients were asked to score their intensity of pain by VRS-5 in 5 degree scale before epidural injection, and report the staring time of analgesia as well as the duration of analgeisa, and score the degree of pain when maximal analgesia was achieved. In the mean time, BP, HR, RR and SaO2 were monitored for a total of 120 min. The results indicate that (1) there was no difference among the 3 groups in the starting time of analgesic effect (3.0±2.0, 3. 0±2. 0, 4. 5±2. 8 min in group A,B and C respectively, x±s). The po tency of analgesia was sighficanily higher in group A as compared to group B (P0.01) and group C (P0.05). The duration of analgesia was A (362±54min)C(246± 41min)B (92±34min). No significant side effects were revealed except for slight somnolence in 6 cases in group A and 4 cases in group B, presumably induced by ketamine.It is concluded that low dose ketamine in combination with low dose bupivacaine for epidural administration is a good method for post-operative analgesia because of its rapid, prolonged and reliable analgesia and slight side effect." @default.
- W2380973722 created "2016-06-24" @default.
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- W2380973722 date "1997-01-01" @default.
- W2380973722 modified "2023-09-25" @default.
- W2380973722 title "EPIDURAL INJECTION OF KETAMINE BUPIVACAINE FOR POST-OPERATIVE ANALGESIA" @default.
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