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- W2381014748 abstract "Objective To observe the effect of Runfu Zhiyang Cream on the proliferation of human epidermal keratinocytes in vitro,and to investigate its influence on P38 mitogen activated protein kinase(P38MAPK) expression.Methods The cell proliferation activity was detected by methyl thiazolyl tetrazolium(MTT) method,and P38MAPK expression was detected by Western blotting in all of the groups.Results Runfu Zhiyang Cream could significantly inhibit the proliferation of keratinocytes,and the effect was similar to that of Tazarotene.Runfu Zhiyang Cream could also inhibit the expression of phosphorylated P38MARK.Conclusion The therapeutic effect of Runfu Zhiyang Cream for psoriasis is probably related with the inhibition of keratinocyte proliferation through suppressing the activation of P38MAPK signal pathway." @default.
- W2381014748 created "2016-06-24" @default.
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- W2381014748 date "2013-01-01" @default.
- W2381014748 modified "2023-09-25" @default.
- W2381014748 title "Effect of Runfu Zhiyang Cream on Keratinocyte Proliferation Through Regulating P38 Mitogen Activated Protein Kinase Pathway" @default.
- W2381014748 hasPublicationYear "2013" @default.
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