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- W2381015523 abstract "The aim of this study was to investigate the effect of active immunization using inhibin α subunit mature peptide(roINH) with Montanide(MON) and Freund's(FA) adjuvants on ovarian development in Xinjiang Fine-wool sheep.72 Sprague Dawley female rats of(9-10)-week-old were divided into 3 groups and actively immunized against the recombination fusion protein of Xinjiang Fine-wool sheep roINH with roINH+MON adjuvant(MON group) or roINH+FA adjuvant(FA group),or injected with physiological saline(control group),respectively.Each rat received a primary immunization and 2 booster immunization at 20-day interval.The results showed that,the antibody titer of MON group was significantly higher than that of FA group(P0.05),compared to controls,mean concentration of FSH was higher(P0.01) in the MON and FA groups,and there was a significant increase in the peak of P in MON and FA groups(P0.05),respectively.For the entire period of the study,mean concentration and peak of FSH and P were of no significant difference between the two immune groups(P0.05);mean concentration and peak of LH between the two immune groups had no significant difference(P0.05).There was no significant increase between MON and FA groups in the number of mature follicle(P0.05),which were both significant higher than that in control group(P0.05).Compared to FA group,the inflammatorial size was smaller and the inflammatory reaction was weaker in MON group.These results clearly demonstrate that active immunization against inhibin α subunit mature peptide in MON or FA adjuvants both can enhance immune effect,furthermore,the inflammatory reaction of MON adjuvant is less than that of FA adjuvant." @default.
- W2381015523 created "2016-06-24" @default.
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- W2381015523 date "2012-01-01" @default.
- W2381015523 modified "2023-09-23" @default.
- W2381015523 title "Effects of Active Immunization against Inhibin on Hormonal Level and Ovarian Development in Rats:Comparison of Montanide and Freund's Adjuvant" @default.
- W2381015523 hasPublicationYear "2012" @default.
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