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- W2381024926 abstract "A method for the determination of metronidazole,clotrimazole and chlorhexidine acetate in compound ointment of Shuangzuotai was established.The RP-HPLC was conducted on a C 18 ODS column with(methanol,water,triethylamine volume ratio 70:30:0.3,consisted of 10 mmol/L sodium sulfonate of heptane,adjusted to pH 4.0 by phosphoric acid) as the mobile phase,detect wavelength at 260 nm.The peak areas and concentrations of metronidazole,clotrimazole and chlorhexidine acetate respectively showed good correlation in the following ranges:3.92～39.2μg/mL(r = 0.9999),3.32～33.2 (r=0.9994),1.64～16.4μg/mL(r=0.999 1).The average recoveries were 99.95%,101.14%and 99.47%(n=9)respectively.The method was simple,sensitive,accurate and suitable for simultaneous determination of three constituents in the compound ointment." @default.
- W2381024926 created "2016-06-24" @default.
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- W2381024926 date "2010-01-01" @default.
- W2381024926 modified "2023-09-24" @default.
- W2381024926 title "Content Determination of Metronidazole,Clotrimazole and Chlorhexidin Acetate in Compound Ointment of Shuangzuotai by RP-HPLC" @default.
- W2381024926 hasPublicationYear "2010" @default.
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